Technology

Magnostics Ltd is a bionanotechnology SME founded on successive research investment by NASA and the EU. We produce the high performance Aurosphere® magnetic beads, which enable rapid, high yield separation for precision medicine.

Superparamagnetic Bead Technology

A breakthrough in performance:

Clinical samples are notoriously difficult to work with using conventional research technics: columns block and nanobeads get lost in viscous fluids. The Aurosphere® superparamagnetic beads are designed specifically for rapid separation from viscous clinical samples and fermentation broths. Large surface areas and small size lead to highly efficient reactions in minutes.

The Aurosphere® beads represent a breakthrough in performance in magnetic separation - the magnetization of these particles is 3-5x higher.

Regarding the separation speed, Aurosphere® 800nm beads (in red below) are faster than competitors' beads that have similar sizes. Considering that the magnetic force is proportional to the cubic of bead’s diameter, the separation speed using Aurosphere® 800nm beads is so fast that they are comparable with competitor’s 2.8μm beads (in yellow).

Aurosphere® beads have been used and described in these publications:

Journal of Applied Physics (Aurosphere® beads were called MagSense)

Nanoscale

Aurosphere® Advantages

Highly Efficient Separation

Our 800 nm beads have 500x reaction rates relative to 2.7 μm beads and the higher magnetic moment results is high yield from even complex media. Higher efficiency separations enables you to isolate rare analytes in complex media.

Quick, Easy, & Convenient

Rates separation increased to 2-3x with manual and automated workflows. More rapid separations increases productivity and enable detection of rare RNA/ DNA.

A Patented Technology

Our technology is patented for nanoparticle synthesis and single particle tracking:
Know how:ISO 13485/GMP processing of the Aurosphere® beads in a cost-efficient manner.
Know how:Surface chemistries for coating beads and making kits for extracting RNA/DNA from complex matrices like blood.

Easy To Use

Kit contains everything you need: beads, all buffers and magnets.

No Microplastics

Aurosphere magnetic beads are based on a polymer-free technology.

Rapid Separation

High Recovery

Reproducibility

A customizable bead

We propose different types of magnetic beads. Different surface coatings and chemistries give each type of bead its own binding properties, making Aurosphere® superparamagnetic beads suitable for various biomedical applications including RNA/DNA isolation for in vitro diagnostics, i.e., RT-qPCR, cell separation and nano-diagnostics.

Our applications

How does magnetic separation work?

Magnetic separation uses magnetic beads to bind targeted biomolecules and separate them from serum and clinical samples. A magnetic force is applied to the sample mixture, and the molecule of interest, which is coated on the magnetic beads, is separated from the mixture.It provides a quick and easy method to purify specific proteins, nucleic acids, and other biomolecules.

See a protocol

Nano-diagnostics for precision medicine

Our superparamagnetic nanoparticle technology enables the detection of a few microorganisms or molecules that would not be possible with conventional techniques. Early detection of disease such as acute mesenteric ischemia or ovarian cancer improves the chances of cure.

Our nano-diagnostics

1 3

Item added to your cart