Protocol
How does magnetic separation work?
Magnetic separation uses magnetic beads to bind targeted biomolecules and separate them from serum and clinical samples. A magnetic force is applied to the sample mixture, and the molecule of interest, which is coated on the magnetic beads, is separated from the mixture.It provides a quick and easy method to purify specific proteins, nucleic acids, and other biomolecules.
Typical magnetic beads enabled protocol
For In vitro Diagnostics, with an extraction of biomarkers from serum and clinical samples:
Step 1: Customize: Tailor your beads to match your application.
Step 2: Mix: Mix nanoparticles with biomarkers’ sample.
Step 3: Bind and extract: Nanoparticles bind to the desired biomarkers. Use a magnetic force to aggregate the bound material.
Step 4: Wash: Remove unbound materials by aspiration, what remains is the nanoparticle-bound targets.
Step 5: Elute: Release the bound target biomarkers from the nanoparticle. The selected biomarkers’ sample is ready for downstream applications.