Publications

Explore Magnostics’ Publications:

Magnetic Separation Publications
Magnostics has demonstrated the superior separation efficiency of its AurosphereTM magnetic beads for the separation of cancer cells, yeast and nucleic acids from complex media and serum.

-Ovarian Cancer Cell Separation for Screening and Staging Diagnostics: Targeting Mucin Protein Enables Rapid and Efficient Ovarian Cancer Cell Capture: Role of Nanoparticle Properties in Efficient Capture and Culture, Nathan Feely, Anita Wdowicz, Anne Chevalier, Ying Wang, Peng Li, Fanny Rollo ad Gil U. Lee, 2023
doi: 10.1002/smll.202207154

-Role of detergents and nuclease inhibitors in the extraction of RNA from eukaryotic cells in complex matrices, Cian Holohan, Nathan Feely, Peng Li, Gerard Curran and Gil U. Lee, 2022.
doi: 10.1039/D2NR02850F

-Influence of viral transport media and freeze-thaw cycling on the sensitivity of qRT-PCR detection of SARS-CoV-2 nucleic acids, Cian Holohan, Sophia Hanrahan, Nathan Feely, Peng Li, John O’Connell, Catherine Moss, Michael Carr, Oya Tagit and Gil U. Lee, 2022
doi: 10.1039/D1NR03933D

- Characterization of carboxylate nanoparticle adhesion with the fungal pathogen Candida albicans, Amy Lyden, Lisa Lombardi, Wilfried Sire, Peng Li, Jeremy C. Simpson, Geraldine Butler and Gil U. Lee, 2017
doi: 10.1039/C7NR04724J

-M13 Bacteriophage-Activated Superparamagnetic Beads for Affinity Separation, Julien Muzard, Mark Platt and Gil U. Lee, 2012
doi: 10.1002/smll.201200099

-Advances in Superparamagnetic-Synthetic Affinity Ligand Functionalized Nanomaterials for Biomagnetic separation, Conor Fields, Peng Li, James J. O’Mahony and Gil U. Lee, 2015
doi: 10.1002/bit.25665

 

Cell Separation Publications

-Ovarian Cancer Cell Separation for Screening and Staging Diagnostics: Targeting Mucin Protein Enables Rapid and Efficient Ovarian Cancer Cell Capture: Role of Nanoparticle Properties in Efficient Capture and Culture, Nathan Feely, Anita Wdowicz, Anne Chevalier, Ying Wang, Peng Li, Fanny Rollo ad Gil U. Lee, 2023
doi: 10.1002/smll.202207154

RNA/DNA Isolation Publications

-Isolation of RNA from serum for high sensitivity RT-qPCR: Influence of viral transport media and freeze-thaw cycling on the sensitivity of qRT-PCR detection of SARS-CoV-2 nucleic acids, Cian Holohan, Sophia Hanrahan, Nathan Feely, Peng Li, John O’Connell, Catherine Moss, Michael Carr, Oya Tagit and Gil U. Lee, 2021
doi:10.1101/2021.06.18.448982

-Micromagnet arrays for on-chip focusing, switching, and separation of superparamagnetic beads and single cells, S. Rampini, D. Kilinc, P. Li, C. Monteil, D. Gandhi and G. U. Lee, 2015.
doi: 10.1039/C5LC00581G

 

Point of Care and Laboratory Assays Publications

Magnostics has demonstrated detection of viruses and specific genetic sequences based on micromagnet arrays. This technology promises the integration of magnetic nanoparticle technology into rapid point of care testing (POCT).

Direct detection of viruses and cells with micromagnetic arrays:

-Design of micromagnetic arrays for on-chip separation of superparamagnetic bead aggregates and detection of a model protein and double-stranded DNA analytes, Stefano Rampini, Peng Li, Dhruv Gandhi, Marina Mutas, Ying-Feng Ran, Michael Carr and Gil U. Lee, 2021
doi:10.1038/s41598-021-84395-3

-Micromagnet arrays for on-chip focusing, switching, and separation of superparamagnetic beads and single cells, S. Rampini, D. Kilinc, P. Li, C. Monteil, D. Gandhi and G. U. Lee, 2015.
doi: 10.1039/C5LC00581G

POCT for Herpes Simplex Virus (HSV-1) with micromagnetic arrays:

-Direct identification of the herpes simplex virus UL27 gene through single particle manipulation and optical detection using a micromagnetic array, Peng Li, Dhruv Gandhi, Marina Mutas, Yin-Fen Ran, Michael Carr, Stefano Rampini, William Hall and Gil U. Lee, 2020
doi: 10.1039/C9NR10362G

-Rapid, highly sensitive detection of herpes simplex virus-1 using multiple antigenic peptide-coated superparamagnetic beads, Ying-Fen Ran, Conor Fields, Julien Muzard, Viktoryia Liauchuk, Michael Carr, William Hall and Gil U. Lee, 2014
doi: 10.1039/C4AN00774C

 

POCT of Cardiac Troponin I with Aurosphere® beads

- Rapid and sensitive detection of cardiac troponin I using a force enhanced immunoassay with nanoporous membrane, G.U. Lee, W.S. Chang, P. Li, S. Kakade, Y. Xiong, H. Shang, Y. Zhang, 2020
doi.org/10.1039/D0NR02234A

 

Ovarian Cancer Publications

-Ovarian Cancer Cell Separation for Screening and Staging Diagnostics: Targeting Mucin Protein Enables Rapid and Efficient Ovarian Cancer Cell Capture: Role of Nanoparticle Properties in Efficient Capture and Culture, Nathan Feely, Anita Wdowicz, Anne Chevalier, Ying Wang, Peng Li, Fanny Rollo ad Gil U. Lee, 2023
doi: 10.1002/smll.202207154

 

Infectious Diseases Publications

-SARS-COV-2: Influence of viral transport media and freeze-thaw cycling on the sensitivity of qRT-PCR detection of SARS-CoV-2 nucleic acids, Cian Holohan, Sophia Hanrahan, Nathan Feely, Peng Li, John O’Connell, Catherine Moss, Michael Carr, Oya Tagit and Gil U. Lee, 2021
doi:10.1101/2021.06.18.448982

-Candida Albicans: Characterization of carboxylate nanoparticle adhesion with the fungal pathogen Candida albicans, Amy Lyden, Lisa Lombardi, Wilfried Sire, Peng Li, Jeremy C. Simpson, Geraldine Butler and Gil U. Lee, 2017
doi: 10.1039/C7NR04724J

-Herpes Simplex Virus (HSV-1): Direct identification of the herpes simplex virus UL27 gene through single particle manipulation and optical detection using a micromagnetic array, Peng Li, Dhruv Gandhi, Marina Mutas, Yin-Fen Ran, Michael Carr, Stefano Rampini, William Hall and Gil U. Lee, 2020
doi: 10.1039/C9NR10362G

-Herpes Simplex Virus (HSV-1): Rapid, highly sensitive detection of herpes simplex virus-1 using multiple antigenic peptide-coated superparamagnetic beads, Ying-Fen Ran, Conor Fields, Julien Muzard, Viktoryia Liauchuk, Michael Carr, William Hall and Gil U. Lee, 2014
doi: 10.1039/C4AN00774C