{"product_id":"aurosphere-800-mesoporous-silica-superparamagnetic-beads","title":"Aurosphere Mesoporous Silica, Superparamagnetic Beads","description":"\u003ch3\u003e\u003cstrong\u003eProduct description \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0755\/3030\/5877\/files\/aurosphere-mesoporous-beads.png?v=1773831602\" alt=\"\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"OutlineElement Ltr SCXW174738276 BCX0\"\u003e\n\u003cp class=\"Paragraph SCXW174738276 BCX0\"\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW174738276 BCX0\"\u003eMagnostics\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003edesigned the\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW174738276 BCX0\"\u003eAurosphere\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003e® 800 mesoporous silica superparamagnetic beads\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003efor high‑performance nucleic acid separation workflows. Their\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003especific surface area is \u003cstrong\u003eover 40 times larger\u003c\/strong\u003e than that of conventional smooth silica beads (Fig 1)\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003e, enabling enhanced interaction between nucleic acids and the silica surface.\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"134233117\":false,\"134233118\":false,\"201341983\":0,\"335559738\":210,\"335559739\":210,\"335559740\":300}' class=\"EOP SCXW174738276 BCX0\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"OutlineElement Ltr SCXW174738276 BCX0\"\u003e\n\u003cp class=\"Paragraph SCXW174738276 BCX0\"\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003eThis characteristic allows highly efficient binding of DNA and RNA (Fig 2), including \u003cstrong\u003eshort fragments \u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003ed\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003e\u003cstrong\u003eown to ~50 bp (even~25 bp \u003c\/strong\u003ewith optimized conditions) from serum, through adsorption within the pores and on the external silica surface (Fig 3).\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"134233117\":false,\"134233118\":false,\"201341983\":0,\"335559738\":210,\"335559739\":210,\"335559740\":300}' class=\"EOP SCXW174738276 BCX0\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"OutlineElement Ltr SCXW174738276 BCX0\"\u003e\n\u003cp class=\"Paragraph SCXW174738276 BCX0\"\u003e\u003cspan class=\"TextRun SCXW174738276 BCX0\" lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW174738276 BCX0\"\u003eThey can be used directly for nucleic acid extraction or further adapted through chemical functionalization for a broad range of life science applications.\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"134233117\":false,\"134233118\":false,\"201341983\":0,\"335559738\":210,\"335559739\":210,\"335559740\":300}' class=\"EOP SCXW174738276 BCX0\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003e\u003cstrong\u003eFeatures  \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003eSpecific surface area\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e:\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e~\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e160 m\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan data-fontsize=\"7\" class=\"NormalTextRun Superscript SCXW171592684 BCX0\"\u003e2\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e\/g\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e(vs. ~3 m\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan data-fontsize=\"6.5\" class=\"NormalTextRun Superscript SCXW171592684 BCX0\"\u003e2\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003e\/g for non-porous beads)) \u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"134233117\":false,\"134233118\":false,\"201341983\":0,\"335559738\":0,\"335559739\":0,\"335559740\":300}' class=\"EOP SCXW171592684 BCX0\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003eUniform size\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"134233117\":false,\"134233118\":false,\"201341983\":0,\"335551550\":1,\"335551620\":1,\"335557856\":16119285,\"335559738\":155,\"335559739\":155,\"335559740\":14}' class=\"EOP SCXW171592684 BCX0\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003eUniform, thick silica coating\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003eRapid, high efficiency separation\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"TextRun SCXW171592684 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW171592684 BCX0\"\u003eChemically inert - sterilizable\u003c\/span\u003e\u003c\/span\u003e          \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\n\u003cstrong\u003eSpecifications \u003c\/strong\u003e               \u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cdiv\u003e\n\u003ctable style=\"width: 99.8188%; height: 98px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 55.7515%; height: 19.6px;\"\u003eNominal diameter\u003c\/td\u003e\n\u003ctd style=\"width: 43.8701%; height: 19.6px;\"\u003eNominal 1200 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 55.7515%; height: 19.6px;\"\u003eSurface functional groups\u003c\/td\u003e\n\u003ctd style=\"width: 43.8701%; height: 19.6px;\"\u003eSi-OH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 55.7515%; height: 19.6px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 43.8701%; height: 19.6px;\"\u003e10 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 55.7515%; height: 19.6px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 43.8701%; height: 19.6px;\"\u003eWater, 0.02% sodium azide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003e\u003cstrong\u003eTypical Applications\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eRNA\/DNA isolation for in vitro diagnostics, i.e., RT-qPCR\u003c\/li\u003e\n\u003cli\u003eGenome isolation – sequencing\u003c\/li\u003e\n\u003cli\u003eIon exchange chromatography\u003c\/li\u003e\n\u003cli\u003eChemical functionalization\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0755\/3030\/5877\/files\/BET-surface-area-aurosphere-mesoporous-beads.png?v=1773831639\" alt=\"\" width=\"289\" height=\"179\"\u003e\u003c\/p\u003e\n\u003ch6\u003e\n\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003eFig 1.\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SpellingErrorHighlight SCXW144799568 BCX0\"\u003eAurosphere\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e® 800 nm\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW144799568 BCX0\"\u003emesoporousbeads\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003e(MB) have a significantly higher specific surface area compared to\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003ethe conventional\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003ebeads (CB). \u003c\/span\u003e\n\u003c\/h6\u003e\n\u003cp\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0755\/3030\/5877\/files\/binding_aurosphere-mesoporous-beads.png?v=1773831688\" alt=\"\" width=\"319\" height=\"199\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch6\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e\u003cspan data-contrast=\"auto\" lang=\"FR-FR\" class=\"TextRun SCXW60033520 BCX0\"\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW60033520 BCX0\"\u003eFig\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW60033520 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003e2.\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-contrast=\"none\" lang=\"EN-US\" class=\"TextRun SCXW60033520 BCX0\"\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW60033520 BCX0\"\u003eAurosphere\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW60033520 BCX0\"\u003e® 800 nm mesoporous beads (streptavidin) extract 2x more biomarkers.\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"LineBreakBlob BlobObject DragDrop SCXW60033520 BCX0\"\u003e\u003cspan class=\"SCXW60033520 BCX0\"\u003e \u003c\/span\u003e\u003cbr class=\"SCXW60033520 BCX0\"\u003e\u003c\/span\u003e\u003cspan data-contrast=\"none\" lang=\"FR-FR\" class=\"TextRun SCXW60033520 BCX0\"\u003e\u003cspan class=\"NormalTextRun SCXW60033520 BCX0\"\u003eCircle:\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW60033520 BCX0\"\u003eMesoporous\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW60033520 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003eBeads\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"LineBreakBlob BlobObject DragDrop SCXW60033520 BCX0\"\u003e\u003cspan class=\"SCXW60033520 BCX0\"\u003e \u003c\/span\u003e\u003cbr class=\"SCXW60033520 BCX0\"\u003e\u003c\/span\u003e\u003cspan data-contrast=\"none\" lang=\"FR-FR\" class=\"TextRun SCXW60033520 BCX0\"\u003e\u003cspan class=\"NormalTextRun SCXW60033520 BCX0\"\u003eTriangle:\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW60033520 BCX0\"\u003eConventional\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW60033520 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW60033520 BCX0\"\u003eBeads\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"EOP SCXW60033520 BCX0\" data-ccp-props=\"{}\"\u003e \u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/h6\u003e\n\u003cp\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e\u003cspan class=\"EOP SCXW60033520 BCX0\" data-ccp-props=\"{}\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0755\/3030\/5877\/files\/gel-image-aurosphere-mesoporous-beads.png?v=1773831731\" alt=\"\" width=\"271\" height=\"228\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch6\u003e\u003cspan class=\"NormalTextRun SCXW144799568 BCX0\"\u003e\u003cspan class=\"EOP SCXW60033520 BCX0\" data-ccp-props=\"{}\"\u003e\u003cspan data-contrast=\"none\" lang=\"EN-US\" class=\"TextRun SCXW95125536 BCX0\"\u003e\u003cspan class=\"NormalTextRun SCXW95125536 BCX0\"\u003eFig 3.\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SpellingErrorV2Themed SCXW95125536 BCX0\"\u003eAurosphere\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW95125536 BCX0\"\u003e® 800 nm mesoporous beads (MB) extract short fragments down to ~50 bp from serum (1) and ~25 bp with optimized conditions)\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-contrast=\"none\" lang=\"EN-US\" class=\"TextRun SCXW95125536 BCX0\"\u003e\u003cspan class=\"NormalTextRun SCXW95125536 BCX0\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan data-contrast=\"none\" lang=\"EN-US\" class=\"TextRun SCXW95125536 BCX0\"\u003e\u003cspan class=\"NormalTextRun SCXW95125536 BCX0\"\u003e(2)\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW95125536 BCX0\"\u003ewhereas\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW95125536 BCX0\"\u003e\u003cspan\u003e \u003c\/span\u003econventional beads (CB) mostly only extract longer fragments (from \u0026gt;100 bp)\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"EOP SCXW95125536 BCX0\" data-ccp-props=\"{}\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/h6\u003e","brand":"Magnostics","offers":[{"title":"800 nm \/ 1 mL (10 mg)","offer_id":51014614417749,"sku":"PN3012A1","price":99.0,"currency_code":"EUR","in_stock":true},{"title":"800 nm \/ 2 mL (20 mg)","offer_id":53480730984789,"sku":"PN3012A2","price":140.0,"currency_code":"EUR","in_stock":true},{"title":"800 nm \/ 5 mL (50 mg)","offer_id":53480731017557,"sku":"PN3012A5","price":260.0,"currency_code":"EUR","in_stock":true},{"title":"800 nm \/ 10 mL (100 mg)","offer_id":53480731050325,"sku":"PN3012A10","price":415.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0755\/3030\/5877\/files\/aurospheresilica_8970db9e-daf0-4b53-a068-c3c0ed4a1448.png?v=1753437358","url":"https:\/\/magnostics.com\/products\/aurosphere-800-mesoporous-silica-superparamagnetic-beads","provider":"Magnostics","version":"1.0","type":"link"}